{"id":61151,"date":"2025-11-21T00:28:20","date_gmt":"2025-11-21T00:28:20","guid":{"rendered":"https:\/\/iarc.spherical.horse\/news-events\/iarc-monographs-evaluation-of-the-carcinogenicity-of-atrazine-alachlor-and-vinclozolin\/"},"modified":"2026-07-16T12:21:08","modified_gmt":"2026-07-16T12:21:08","slug":"iarc-monographs-evaluation-of-the-carcinogenicity-of-atrazine-alachlor-and-vinclozolin","status":"publish","type":"news-events","link":"https:\/\/iarc.spherical.horse\/fr\/news-events\/iarc-monographs-evaluation-of-the-carcinogenicity-of-atrazine-alachlor-and-vinclozolin\/","title":{"rendered":"Volume 140 : Atrazine, alachlore et vinclozoline"},"content":{"rendered":"<p>Les r\u00e9sultats de la r\u00e9cente \u00e9valuation par les\u00a0<em>Monographies du CIRC<\/em>\u00a0de la canc\u00e9rog\u00e9nicit\u00e9 de trois pesticides \u2013 les herbicides atrazine et alachlore, et le fongicide vinclozoline \u2013 ont \u00e9t\u00e9 publi\u00e9s dans la revue\u00a0<em>The Lancet Oncology<\/em>. Cet article r\u00e9sume les conclusions de la R\u00e9union 140 des\u00a0<em>Monographies du CIRC<\/em>.<\/p>\r\n<p>L\u2019atrazine a \u00e9t\u00e9 pr\u00e9c\u00e9demment \u00e9valu\u00e9e en 1998 dans le Volume 73 des <em>Monographies du CIRC<\/em>. Il s\u2019agissait de la premi\u00e8re \u00e9valuation pour l\u2019alachlore et la vinclozoline.<\/p>\r\n<p>Les herbicides atrazine et alachlore ont \u00e9t\u00e9 largement utilis\u00e9s dans le monde pour le d\u00e9sherbage des pelouses et des cultures comme le ma\u00efs. La vinclozoline est un fongicide utilis\u00e9 dans l\u2019agriculture, principalement pour la culture des fruits et des l\u00e9gumes.<\/p>\r\n<p>Le Groupe de travail a \u00e9valu\u00e9 l\u2019atrazine et l\u2019alachlore comme \u00ab\u00a0probablement canc\u00e9rog\u00e8nes pour l\u2019homme\u00a0\u00bb (Groupe\u00a02A) sur la base des combinations (i) d\u2019indications \u00ab\u00a0limit\u00e9es\u00a0\u00bb de cancer chez l\u2019homme et d\u2019indications \u00ab\u00a0suffisantes\u00a0\u00bb de cancer chez l\u2019animal de laboratoire\u00a0; et (ii) d\u2019indications \u00ab\u00a0limit\u00e9es\u00a0\u00bb de cancer chez l\u2019homme et d\u2019indications m\u00e9canistiques \u00ab\u00a0fortes\u00a0\u00bb dans les syst\u00e8mes exp\u00e9rimentaux. Pour l\u2019atrazine, des associations positives ont \u00e9t\u00e9 observ\u00e9es pour le lymphome non hodgkinien positif pour la translocation chromosomique t(14;18). Des associations positives ont \u00e9t\u00e9 observ\u00e9es entre l\u2019alachlore et le cancer du larynx.<\/p>\r\n<p>La vinclozoline a \u00e9t\u00e9 class\u00e9e comme \u00ab\u00a0peut-\u00eatre canc\u00e9rog\u00e8ne pour l\u2019homme\u00a0\u00bb (Group\u00a02B) sur la base d\u2019indications \u00ab\u00a0suffisantes\u00a0\u00bb de cancer chez l\u2019animal de laboratoire et d\u2019indications m\u00e9canistiques \u00ab\u00a0fortes\u00a0\u00bb dans les syst\u00e8mes exp\u00e9rimentaux. Les indications relatives au cancer chez l\u2019homme \u00e9taient \u00ab\u00a0insuffisantes\u00a0\u00bb.<\/p>\r\n<p>L\u2019int\u00e9gralit\u00e9 des \u00e9valuations scientifiques sera publi\u00e9e dans le Volume 140 des <em>Monographies du CIRC<\/em>.<\/p>\r\n<p>Cattley RC, De Roos AJ, Mandrioli D, Pearce N, Pronk A, Soshilov A, et al.<br \/>\r\nCarcinogenicity of atrazine, alachlor, and vinclozolin<br \/>\r\n<em>Lancet Oncol<\/em>. publi\u00e9 en ligne le 21 novembre 2025 ; <br \/>\r\nhttps:\/\/doi.org\/10.1016\/S1470-2045(25)00702-8<\/p>\r\n<p><a href=\"https:\/\/www.thelancet.com\/journals\/lanonc\/article\/PIIS1470-2045(25)00702-8\/fulltext\" target=\"_blank\" rel=\"noopener noreferrer\">Lire l\u2019article <\/a><\/p>\r\n<p><a href=\"\/wp-content\/uploads\/2025\/11\/QA-Mono-Vol140.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Lire les FAQ <\/a><\/p>\r\n<p><a href=\"\/wp-content\/uploads\/2025\/11\/infographic_mono_vol_140.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">Voir l\u2019infographie <\/a><\/p>\r\n<p><a href=\"\/video\/iarc-monographs-evaluation-of-the-carcinogenicity-of-atrazine-alachlor-and-vinclozolin\/\">Voir les vid\u00e9os <\/a><\/p>","protected":false},"featured_media":42920,"template":"","class_list":["post-61151","news-events","type-news-events","status-publish","has-post-thumbnail","hentry","cancer-site_taxonomy-head-and-neck-cancer-fr","cancer-site_taxonomy-non-hodgkin-lymphoma-fr","research-topic_taxonomy-cancer-hazard-identification-fr","risk-factor_taxonomy-environmental-exposures-fr","risk-factor_taxonomy-occupational-exposures-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events\/61151","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events"}],"about":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/types\/news-events"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media\/42920"}],"wp:attachment":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media?parent=61151"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}