{"id":58482,"date":"2025-02-14T12:11:07","date_gmt":"2025-02-14T12:11:07","guid":{"rendered":"https:\/\/iarc.spherical.horse\/news-events\/iarc-monographs-volume-135-perfluorooctanoic-acid-pfoa-and-perfluorooctanesulfonic-acid-pfos\/"},"modified":"2026-06-30T13:59:23","modified_gmt":"2026-06-30T13:59:23","slug":"iarc-monographs-volume-135-perfluorooctanoic-acid-pfoa-and-perfluorooctanesulfonic-acid-pfos","status":"publish","type":"news-events","link":"https:\/\/iarc.spherical.horse\/fr\/news-events\/iarc-monographs-volume-135-perfluorooctanoic-acid-pfoa-and-perfluorooctanesulfonic-acid-pfos\/","title":{"rendered":"<em>IARC Monographs<\/em> Volume 135: Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS)"},"content":{"rendered":"<p>The International Agency for Research on Cancer (IARC) is pleased to announce that Volume 135 of the <em>IARC Monographs<\/em> is now available online. This volume comprises a single monograph covering both perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS).<\/p>\r\n<p>PFOA and PFOS are per- and polyfluoroalkyl substances (PFAS) that are extremely resistant to degradation. First produced in the 1940s, PFOA has extensive uses, including in fluoropolymer manufacture and applications; in surface coatings conferring resistance to stains, oil, and water on household products, carpets, textiles, leather products, and food and feed packaging; in electrics and electronics; and in construction materials. With some similar uses to those of PFOA, PFOS additionally has applications in aqueous film-forming foams used in firefighting; in the fabrication of imaging devices and semiconductors; in photolithography and electroplating; and in insulation, dyes, and ink.<\/p>\r\n<p>The Working Group evaluated PFOA as <em>carcinogenic to humans<\/em> (Group 1) on the basis of <em>sufficient<\/em> evidence for cancer in experimental animals and <em>strong<\/em> mechanistic evidence that PFOA exhibits key characteristics of carcinogens in exposed humans. There was <em>limited<\/em> evidence in humans for cancer of the testis and for renal cell carcinoma. PFOS was evaluated as <em>possibly carcinogenic to humans<\/em> (Group 2B) on the basis of <em>strong<\/em> mechanistic evidence for key characteristics of carcinogens, including in exposed humans. There was <em>limited<\/em> evidence for cancer in experimental animals and <em>inadequate<\/em> evidence for cancer in humans for PFOS.<br \/>\r\n<br \/>\r\n<a href=\"https:\/\/publications.iarc.who.int\/636\" target=\"_blank\" rel=\"noopener noreferrer\">Visit the Volume 135 webpage<\/a><br \/>\r\n<\/p>","protected":false},"featured_media":58483,"template":"","class_list":["post-58482","news-events","type-news-events","status-publish","has-post-thumbnail","hentry","cancer-site_taxonomy-kidney-cancer-fr","cancer-site_taxonomy-testicular-cancer-fr","research-topic_taxonomy-cancer-hazard-identification-fr","risk-factor_taxonomy-dietary-exposures-fr","risk-factor_taxonomy-environmental-exposures-fr","risk-factor_taxonomy-occupational-exposures-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events\/58482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events"}],"about":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/types\/news-events"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media\/58483"}],"wp:attachment":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media?parent=58482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}