{"id":46841,"date":"2022-05-10T00:23:37","date_gmt":"2022-05-10T00:23:37","guid":{"rendered":"https:\/\/iarc.spherical.horse\/news-events\/treatment-guideline-concordance-abc-do\/"},"modified":"2022-05-10T07:01:39","modified_gmt":"2022-05-10T07:01:39","slug":"treatment-guideline-concordance-abc-do","status":"publish","type":"news-events","link":"https:\/\/iarc.spherical.horse\/fr\/news-events\/treatment-guideline-concordance-abc-do\/","title":{"rendered":"Treatment guideline concordance, initiation, and abandonment in patients with non-metastatic breast cancer from the African Breast Cancer\u2013Disparities in Outcomes (ABC-DO) cohort in sub-Saharan Africa: a prospective cohort study"},"content":{"rendered":"<p>Researchers from the International Agency for Research on Cancer (IARC) and partner institutions found that only two thirds of women in sub-Saharan Africa who required chemotherapy to treat breast cancer received treatment in line with guidelines, and that only 1 in 3 of these women adequately completed their treatment. At least 1 in 5 women abandoned their treatment. These results are reported in a new analysis of breast cancer management, guideline concordance, and treatment abandonment in sub-Saharan Africa, from the African Breast Cancer \u2013 Disparities in Outcomes (ABC-DO) study. The article was published in <em>The Lancet Oncology<\/em>.<\/p>\r\n<p>This study is based on more than 1700 patients with breast cancer from seven population groups, diagnosed with non-metastatic invasive breast cancer. During a median follow-up of 5.2 years, multimodality treatment consisting of surgery and systemic therapy with or without radiotherapy was initiated in 74% of women with localized tumours compared with 47% of women with locally advanced tumours. Of the 66% of patients who initiated a guideline-concordant chemotherapy regimen, only 35% adequately completed the treatment course, whereas 24% only marginally completed the course and 20% abandoned treatment. Completion was unknown in 15% of women. There were pronounced differences between populations. The highest treatment initiation rates were recorded in Namibia and South Africa, and the lowest rates were recorded in Nigeria.<\/p>\r\n<p>This study provides a detailed description of current breast cancer management in sub-Saharan Africa, which is the region with the lowest survival rates for patients with breast cancer in the world. The authors identified population-specific treatment gaps and needs, which will help in shaping strategic interventions to provide timely high-quality breast cancer treatment in the region, as called for by the World Health Organization\u2019s Global Breast Cancer Initiative.<\/p>\r\n<p>Foerster M, McCormack V, Anderson BO, Boucheron P, Zietsman A, Cubasch H, et al.<br \/>\r\nTreatment guideline concordance, initiation, and abandonment in patients with non-metastatic breast cancer from the African Breast Cancer\u2013Disparities in Outcomes (ABC-DO) cohort in sub-Saharan Africa: a prospective cohort study<br \/>\r\n<em>Lancet Oncol<\/em>, Published online 9 May 2022;<br \/>\r\nhttps:\/\/doi.org\/10.1016\/S1470-2045(22)00198-X<\/p>\r\n<p><a href=\"https:\/\/doi.org\/10.1016\/S1470-2045(22)00198-X\" target=\"_blank\" rel=\"noopener noreferrer\">Read the article<\/a>\u00a0<\/p>","protected":false},"featured_media":42920,"template":"","class_list":["post-46841","news-events","type-news-events","status-publish","has-post-thumbnail","hentry","country_taxonomy-namibia-fr","country_taxonomy-nigeria-fr","country_taxonomy-south-africa-fr","cancer-site_taxonomy-breast-cancer-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events\/46841","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events"}],"about":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/types\/news-events"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media\/42920"}],"wp:attachment":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media?parent=46841"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}