{"id":37972,"date":"2020-11-27T00:53:51","date_gmt":"2020-11-27T00:53:51","guid":{"rendered":"https:\/\/www.iarc.fr\/news-events\/iarc-monographs-evaluation-of-the-carcinogenicity-of-acrolein-crotonaldehyde-and-arecoline\/"},"modified":"2021-07-29T11:07:22","modified_gmt":"2021-07-29T11:07:22","slug":"iarc-monographs-evaluation-of-the-carcinogenicity-of-acrolein-crotonaldehyde-and-arecoline","status":"publish","type":"news-events","link":"https:\/\/iarc.spherical.horse\/fr\/news-events\/iarc-monographs-evaluation-of-the-carcinogenicity-of-acrolein-crotonaldehyde-and-arecoline\/","title":{"rendered":"<em>IARC Monographs<\/em> evaluation of the carcinogenicity of acrolein, crotonaldehyde, and arecoline"},"content":{"rendered":"<p>The results of the recent <em>IARC Monographs<\/em> evaluation of the carcinogenicity of acrolein, crotonaldehyde, and arecoline have now been published in\u00a0<em>The Lancet Oncology<\/em>. This summary article presents the conclusions of <em>IARC Monographs<\/em> Meeting 128.<\/p>\r\n<p>Acrolein and crotonaldehyde were previously evaluated by the Working Group in 1995. Arecoline was evaluated by the Working Group for the first time.<\/p>\r\n<p>Acrolein and crotonaldehyde are industrial chemicals with a high production volume that are also present in tobacco smoke, in ambient air pollution, and in some cooking oils heated to a high temperature. Arecoline is the primary active ingredient of the areca nut. The Working Group evaluated acrolein as <em>probably<\/em> <em>carcinogenic to humans<\/em> <em>(Group 2A) <\/em>on the basis of <em>sufficient<\/em> <em>evidence<\/em> for carcinogenicity in experimental animals and <em>strong<\/em> mechanistic evidence. Crotonaldehyde and arecoline were classified as <em>possibly<\/em> <em>carcinogenic to humans<\/em> <em>(Group 2B)<\/em> on the basis of <em>strong <\/em>mechanistic evidence.<\/p>\r\n<p>The full scientific assessment will be published as Volume 128 of the\u00a0<em>IARC Monographs<\/em>.<\/p>\r\n<p><em>IARC Monographs<\/em>\u00a0Volume 128 Working Group<br \/>\r\nCarcinogenicity of acrolein, crotonaldehyde, and arecoline<br \/>\r\n<em>Lancet Oncol<\/em>, Published online 26 November 2020;<br \/>\r\nhttps:\/\/doi.org\/10.1016\/S1470-2045(20)30727-0<\/p>\r\n<p><a href=\"https:\/\/doi.org\/10.1016\/S1470-2045(20)30727-0\" target=\"_blank\" rel=\"noopener noreferrer\">Read the\u00a0article<\/a><\/p>\r\n<p><a href=\"\/faq\/iarc-monographs-meeting-128-acrolein-crotonaldehyde-and-arecoline\/\">Read the\u00a0Q&amp;A<\/a><\/p>\r\n<p><a href=\"\/wp-content\/uploads\/2020\/11\/IARC_mono_vol_128_infographic.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">View the\u00a0infographic<\/a><\/p>","protected":false},"featured_media":42920,"template":"","class_list":["post-37972","news-events","type-news-events","status-publish","has-post-thumbnail","hentry","risk-factor_taxonomy-dietary-exposures-fr","risk-factor_taxonomy-environmental-exposures-fr","risk-factor_taxonomy-tobacco-fr"],"acf":[],"_links":{"self":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events\/37972","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/news-events"}],"about":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/types\/news-events"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media\/42920"}],"wp:attachment":[{"href":"https:\/\/iarc.spherical.horse\/fr\/wp-json\/wp\/v2\/media?parent=37972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}